Kcnj2 - potassium inwardly-rectifying channel, subfamily J, member 2

Enables identical protein binding activity. Acts upstream of or within cardiac muscle cell action potential and magnesium ion transport. Predicted to be located in several cellular components, including T-tubule; endoplasmic reticulum; and intercalated disc. Predicted to be intrinsic component of membrane. Predicted to be part of voltage-gated potassium channel complex. Predicted to be active in plasma membrane. Is expressed in several structures, including alimentary system; brain; genitourinary system; heart; and sensory organ. Human ortholog(s) of this gene implicated in Andersen-Tawil syndrome; familial atrial fibrillation; familial periodic paralysis; and short QT syndrome. Orthologous to human KCNJ2 (potassium inwardly rectifying channel subfamily J member 2). [provided by Alliance of Genome Resources, Apr 2022]