Kcnj11 - potassium inwardly rectifying channel, subfamily J, member 11

Enables ATP binding activity; ATP-activated inward rectifier potassium channel activity; and ankyrin binding activity. Involved in potassium ion import across plasma membrane. Located in T-tubule. Part of inward rectifying potassium channel. Is expressed in several structures, including brain; cardiovascular system; gut; skeletal muscle tissue; and testis. Used to study permanent neonatal diabetes mellitus. Human ortholog(s) of this gene implicated in familial hyperinsulinemic hypoglycemia 2 and glucose metabolism disease (multiple). Orthologous to human KCNJ11 (potassium inwardly rectifying channel subfamily J member 11). [provided by Alliance of Genome Resources, Apr 2022]