Kcnj10 - potassium inwardly-rectifying channel, subfamily J, member 10
Alias:
BIR10
BIRK-1
Kir1.2
Kir4.1
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Basic Information
Sequence Homology
Transcripts & Proteins
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Enables inward rectifier potassium channel activity. Involved in non-motile cilium assembly. Acts upstream of or within several processes, including adult walking behavior; ion transmembrane transport; and regulation of resting membrane potential. Located in astrocyte projection; basolateral plasma membrane; and cell body. Is active in ciliary base. Is expressed in several structures, including brain; genitourinary system; spinal cord; stomach; and stria vascularis. Used to study EAST syndrome. Human ortholog(s) of this gene implicated in EAST syndrome and autosomal recessive nonsyndromic deafness 4. Orthologous to human KCNJ10 (potassium inwardly rectifying channel subfamily J member 10). [provided by Alliance of Genome Resources, Apr 2022]