Kcnh2 - potassium voltage-gated channel, subfamily H (eag-related), member 2

Enables inward rectifier potassium channel activity. Acts upstream of or within potassium ion transmembrane transport; regulation of heart rate by cardiac conduction; and regulation of ventricular cardiac muscle cell membrane repolarization. Located in cytoplasm; nuclear envelope; and plasma membrane. Is expressed in several structures, including brain; early conceptus; gonad; heart; and retina. Used to study short QT syndrome. Human ortholog(s) of this gene implicated in long QT syndrome; long QT syndrome 2; and short QT syndrome. Orthologous to human KCNH2 (potassium voltage-gated channel subfamily H member 2). [provided by Alliance of Genome Resources, Apr 2022]