Kcna2 - potassium voltage-gated channel, shaker-related subfamily, member 2

Enables voltage-gated potassium channel activity. Involved in potassium ion transmembrane transport; regulation of circadian sleep/wake cycle, non-REM sleep; and regulation of dopamine secretion. Acts upstream of or within optic nerve structural organization. Located in several cellular components, including axon; neuronal cell body membrane; and perikaryon. Is integral component of plasma membrane. Part of voltage-gated potassium channel complex. Is expressed in brain; heart ventricle; hindlimb muscle; and thalamus mantle layer. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 32. Orthologous to human KCNA2 (potassium voltage-gated channel subfamily A member 2). [provided by Alliance of Genome Resources, Apr 2022]