Jag2 - jagged 2

Enables Notch binding activity. Involved in auditory receptor cell fate commitment; gamma-delta T cell differentiation; and positive regulation of Notch signaling pathway. Acts upstream of or within several processes, including epithelial cell apoptotic process involved in palatal shelf morphogenesis; odontogenesis of dentin-containing tooth; and respiratory system process. Located in membrane. Is integral component of plasma membrane. Is expressed in several structures, including alimentary system; central nervous system; respiratory system; sensory organ; and surface ectoderm. Orthologous to human JAG2 (jagged canonical Notch ligand 2). [provided by Alliance of Genome Resources, Apr 2022]