Predicted to enable several functions, including ICAM-3 receptor activity; amyloid-beta binding activity; and integrin binding activity. Predicted to contribute to cell adhesion molecule binding activity. Predicted to be involved in several processes, including integrin-mediated signaling pathway; leukocyte migration; and regulation of cellular biosynthetic process. Predicted to act upstream of or within inflammatory response. Located in secretory granule. Human ortholog(s) of this gene implicated in coronary restenosis; leukocyte adhesion deficiency; and leukocyte adhesion deficiency 1. Orthologous to human ITGB2 (integrin subunit beta 2). [provided by Alliance of Genome Resources, Apr 2022]