Il1r2 - interleukin 1 receptor, type II

Enables interleukin-1 binding activity and interleukin-1 receptor activity. Acts upstream of or within negative regulation of gene expression and negative regulation of interleukin-1-mediated signaling pathway. Located in cytoplasm. Is expressed in several structures, including dorsal aorta; gut; pituitary gland; reproductive system; and thymus. Human ortholog(s) of this gene implicated in aggressive periodontitis. Orthologous to human IL1R2 (interleukin 1 receptor type 2). [provided by Alliance of Genome Resources, Apr 2022]