Il10ra - interleukin 10 receptor, alpha

Predicted to enable interleukin-10 binding activity and interleukin-10 receptor activity. Predicted to be involved in several processes, including negative regulation of autophagy; positive regulation of receptor signaling pathway via JAK-STAT; and ubiquitin-dependent endocytosis. Predicted to be located in cytosol. Predicted to be integral component of plasma membrane. Predicted to colocalize with plasma membrane. Human ortholog(s) of this gene implicated in inflammatory bowel disease 28. Orthologous to human IL10RA (interleukin 10 receptor subunit alpha). [provided by Alliance of Genome Resources, Apr 2022]