Ccn1 - cellular communication network factor 1

Enables extracellular matrix binding activity and integrin binding activity. Acts upstream of or within several processes, including circulatory system development; positive regulation of hydrolase activity; and regulation of apoptotic process. Located in collagen-containing extracellular matrix. Is expressed in several structures, including brain; cardiovascular system; embryo mesenchyme; sensory organ; and skeleton. Used to study atrial heart septal defect 1 and atrioventricular septal defect. Orthologous to human CCN1 (cellular communication network factor 1). [provided by Alliance of Genome Resources, Apr 2022]