Cldn16 - claudin 16

Predicted to enable identical protein binding activity. Involved in positive regulation of calcium ion transport and transepithelial transport. Located in bicellular tight junction. Used to study hypertension. Human ortholog(s) of this gene implicated in renal hypomagnesemia 3 and renal tubular transport disease. Orthologous to human CLDN16 (claudin 16). [provided by Alliance of Genome Resources, Apr 2022]