Hsd3b5 - hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 5

Predicted to enable 3-beta-hydroxy-delta5-steroid dehydrogenase activity and steroid delta-isomerase activity. Acts upstream of or within response to stilbenoid. Located in mitochondrial inner membrane. Is expressed in several structures, including adrenal gland; gut; liver and biliary system; metanephros; and skeletal muscle. Human ortholog(s) of this gene implicated in hypertension and hypospadias. Orthologous to human HSD3B1 (hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1) and HSD3B2 (hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2). [provided by Alliance of Genome Resources, Apr 2022]