Hsd11b2 - hydroxysteroid 11-beta dehydrogenase 2

Predicted to enable NAD binding activity and steroid binding activity. Acts upstream of or within female pregnancy. Predicted to be located in cytoplasm; lipid droplet; and nucleoplasm. Is expressed in several structures, including adrenal gland; ear; genitourinary system; hemolymphoid system; and nervous system. Human ortholog(s) of this gene implicated in apparent mineralocorticoid excess syndrome; hypertension; inherited metabolic disorder; obesity; and type 1 diabetes mellitus. Orthologous to human HSD11B2 (hydroxysteroid 11-beta dehydrogenase 2). [provided by Alliance of Genome Resources, Apr 2022]