Enables protein serine/threonine kinase activity. Involved in negative regulation of JUN kinase activity; peptidyl-serine phosphorylation; and peptidyl-threonine phosphorylation. Located in PML body and cytoplasm. Is expressed in diaphragm; heart; limb segment; paraxial mesenchyme; and skeletal musculature. Orthologous to human HIPK3 (homeodomain interacting protein kinase 3). [provided by Alliance of Genome Resources, Apr 2022]