Hgs - HGF-regulated tyrosine kinase substrate

Enables identical protein binding activity and ubiquitin-dependent protein binding activity. Predicted to be involved in several processes, including lysosomal transport; negative regulation of signal transduction; and positive regulation of exosomal secretion. Predicted to act upstream of or within protein transport. Located in cytoplasm. Is expressed in several structures, including central nervous system; genitourinary system; olfactory epithelium; retina layer; and spleen. Orthologous to human HGS (hepatocyte growth factor-regulated tyrosine kinase substrate). [provided by Alliance of Genome Resources, Apr 2022]