Hdc - histidine decarboxylase

Enables histidine decarboxylase activity. Acts upstream of or within histamine biosynthetic process and histidine catabolic process. Predicted to be located in cytosol; dendrite; and neuronal cell body. Predicted to be active in cytoplasm. Is expressed in several structures, including alimentary system; brain; genitourinary system; heart; and respiratory system. Used to study Gilles de la Tourette syndrome. Human ortholog(s) of this gene implicated in Gilles de la Tourette syndrome; asthma; and rhinitis. Orthologous to human HDC (histidine decarboxylase). [provided by Alliance of Genome Resources, Apr 2022]