Hcn2 - hyperpolarization-activated, cyclic nucleotide-gated K+ 2

Predicted to enable several functions, including PDZ domain binding activity; cation channel activity; and identical protein binding activity. Acts upstream of or within regulation of membrane potential. Predicted to be located in several cellular components, including axon; dendrite; and neuronal cell body. Predicted to be integral component of plasma membrane. Predicted to be part of HCN channel complex. Is expressed in heart; heart ventricle; spinal cord; and ventral grey horn. Human ortholog(s) of this gene implicated in familial febrile seizures 2. Orthologous to human HCN2 (hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2). [provided by Alliance of Genome Resources, Apr 2022]