Mouse
Hcn1 - hyperpolarization activated cyclic nucleotide gated potassium channel 1
Alias:
HAC2
Bcng1
C630013B14Rik
Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
Enables cAMP binding activity; cation channel activity; and identical protein binding activity. Involved in cellular response to cAMP and potassium ion transmembrane transport. Acts upstream of or within apical protein localization and retinal cone cell development. Located in axon and dendrite. Is integral component of plasma membrane. Is expressed in brain; heart; and heart ventricle. Used to study sick sinus syndrome. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 24 and generalized epilepsy with febrile seizures plus 10. Orthologous to human HCN1 (hyperpolarization activated cyclic nucleotide gated potassium channel 1). [provided by Alliance of Genome Resources, Apr 2022]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
1
8
378709 bp
102.43
9
13
Hcn1 Genetics information (+)
GRCm39
Chr : -
Sequence Homology
Transcripts & Proteins
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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
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Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
No data available
References Literature
Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
Al agent
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