Hbb-bh1 - hemoglobin Z, beta-like embryonic chain

Predicted to enable several functions, including heme binding activity; hemoglobin alpha binding activity; and oxygen carrier activity. Predicted to contribute to haptoglobin binding activity and peroxidase activity. Acts upstream of or within negative regulation of transcription by RNA polymerase II. Predicted to be part of haptoglobin-hemoglobin complex and hemoglobin complex. Is expressed in several structures, including blood; dorsal aorta; extraembryonic component; genitourinary system; and tail bud. Human ortholog(s) of this gene implicated in delta beta-thalassemia and sickle cell anemia. Orthologous to human HBG1 (hemoglobin subunit gamma 1) and HBG2 (hemoglobin subunit gamma 2). [provided by Alliance of Genome Resources, Apr 2022]