H2-DMb2 - histocompatibility 2, class II, locus Mb2

Predicted to enable MHC class II protein complex binding activity. Acts upstream of or within antigen processing and presentation of exogenous peptide antigen via MHC class II and chaperone cofactor-dependent protein refolding. Located in endosome membrane; lysosomal membrane; and multivesicular body. Is integral component of membrane. Orthologous to human HLA-DMB (major histocompatibility complex, class II, DM beta). [provided by Alliance of Genome Resources, Apr 2022]