Gnb5 - guanine nucleotide binding protein (G protein), beta 5

Predicted to enable several functions, including G-protein gamma-subunit binding activity; GTPase activating protein binding activity; and chaperone binding activity. Predicted to contribute to GTPase activator activity. Acts upstream of or within G protein-coupled receptor signaling pathway; dark adaptation; and light adaption. Located in several cellular components, including nucleus; photoreceptor inner segment; and photoreceptor outer segment. Is active in presynapse. Is expressed in several structures, including brain; eye; genitourinary system; liver; and lung. Human ortholog(s) of this gene implicated in intellectual developmental disorder with cardiac arrhythmia. Orthologous to human GNB5 (G protein subunit beta 5). [provided by Alliance of Genome Resources, Apr 2022]