Gna12 - guanine nucleotide binding protein, alpha 12

Predicted to enable D5 dopamine receptor binding activity; G-protein beta/gamma-subunit complex binding activity; and GTPase activity. Involved in several processes, including multicellular organism aging; regulation of TOR signaling; and regulation of fibroblast migration. Acts upstream of or within several processes, including Rho protein signal transduction; embryonic digit morphogenesis; and regulation of cell shape. Predicted to be located in cytoplasm and plasma membrane. Predicted to be part of heterotrimeric G-protein complex. Predicted to be active in brush border membrane. Is expressed in several structures, including branchial arch; central nervous system; female reproductive system; heart; and retina. Orthologous to human GNA12 (G protein subunit alpha 12). [provided by Alliance of Genome Resources, Apr 2022]