Opn1mw - opsin 1 (cone pigments), medium-wave-sensitive (color blindness, deutan)

Predicted to enable G protein-coupled photoreceptor activity and identical protein binding activity. Predicted to be involved in G protein-coupled receptor signaling pathway; cellular response to light stimulus; and phototransduction. Predicted to act upstream of or within protein-chromophore linkage and signal transduction. Located in photoreceptor outer segment. Is expressed in eye; photoreceptor layer; photoreceptor layer outer segment; retina; and retina outer nuclear layer. Used to study blue cone monochromacy. Human ortholog(s) of this gene implicated in blue cone monochromacy and red color blindness. Orthologous to several human genes including OPN1LW (opsin 1, long wave sensitive) and OPN1MW2 (opsin 1, medium wave sensitive 2). [provided by Alliance of Genome Resources, Apr 2022]