Enables glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity. Involved in flagellated sperm motility. Acts upstream of or within glycolytic process. Located in sperm fibrous sheath and sperm principal piece. Human ortholog(s) of this gene implicated in Alzheimer's disease. Orthologous to human GAPDHS (glyceraldehyde-3-phosphate dehydrogenase, spermatogenic). [provided by Alliance of Genome Resources, Apr 2022]