Gabre - gamma-aminobutyric acid (GABA) A receptor, subunit epsilon

Predicted to enable GABA-gated chloride ion channel activity; inhibitory extracellular ligand-gated ion channel activity; and transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to contribute to GABA-A receptor activity; benzodiazepine receptor activity; and chloride channel activity. Predicted to be involved in several processes, including GABAergic synaptic transmission; chloride transmembrane transport; and negative regulation of chloride transport. Predicted to act upstream of or within chloride transport. Predicted to be part of GABA-A receptor complex. Predicted to be active in dendrite membrane and postsynapse. Predicted to be integral component of plasma membrane. Is expressed in several structures, including heart; limb; nervous system; skeleton; and urinary system. Orthologous to human GABRE (gamma-aminobutyric acid type A receptor subunit epsilon). [provided by Alliance of Genome Resources, Apr 2022]