Gabrb2 - gamma-aminobutyric acid (GABA) A receptor, subunit beta 2

Enables transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential. Contributes to GABA-gated chloride ion channel activity. Involved in several processes, including inner ear development; nervous system development; and sensory perception of sound. Located in plasma membrane. Is active in GABA-ergic synapse. Is integral component of postsynaptic specialization membrane. Is expressed in several structures, including alimentary system; heart; integumental system; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in autistic disorder and developmental and epileptic encephalopathy 92. Orthologous to human GABRB2 (gamma-aminobutyric acid type A receptor subunit beta2). [provided by Alliance of Genome Resources, Apr 2022]