G6pdx - glucose-6-phosphate dehydrogenase X-linked

Enables glucose-6-phosphate dehydrogenase activity and identical protein binding activity. Acts upstream of or within several processes, including NADP biosynthetic process; erythrocyte development; and maintenance of blood vessel diameter homeostasis by renin-angiotensin. Predicted to be located in several cellular components, including centriolar satellite; cytoplasmic side of plasma membrane; and cytosol. Is expressed in several structures, including adipose tissue; genitourinary system; immune system; liver; and mammary gland. Used to study favism. Human ortholog(s) of this gene implicated in several diseases, including anemia (multiple); cerebrovascular disease; favism; malaria (multiple); and neonatal jaundice. Orthologous to human G6PD (glucose-6-phosphate dehydrogenase). [provided by Alliance of Genome Resources, Apr 2022]