Fzd5 - frizzled class receptor 5

Enables Wnt-protein binding activity. Involved in camera-type eye development; canonical Wnt signaling pathway; and positive regulation of cytokine production. Acts upstream of or within several processes, including chorionic trophoblast cell differentiation; embryonic organ development; and positive regulation of nitrogen compound metabolic process. Located in several cellular components, including Golgi apparatus; bicellular tight junction; and perinuclear region of cytoplasm. Colocalizes with early endosome. Is expressed in several structures, including alimentary system; early conceptus; future brain; genitourinary system; and sensory organ. Orthologous to human FZD5 (frizzled class receptor 5). [provided by Alliance of Genome Resources, Apr 2022]