Myh7 - myosin, heavy polypeptide 7, cardiac muscle, beta
Alias:
B-MHC
Myhcb
MyHC-I
Myhc-b
betaMHC
beta-MHC
myHC-beta
myHC-slow
MYH-beta/slow
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Description
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
Predicted to enable several functions, including ATP binding activity; ATP hydrolysis activity; and identical protein binding activity. Acts upstream of or within cardiac muscle hypertrophy in response to stress and transition between fast and slow fiber. Located in Z disc and stress fiber. Part of myosin complex. Is expressed in several structures, including diaphragm; eye; heart; musculature; and somite. Human ortholog(s) of this gene implicated in cardiomyopathy (multiple); congenital heart disease (multiple); distal myopathy 1; and hyaline body myopathy (multiple). Orthologous to human MYH7 (myosin heavy chain 7). [provided by Alliance of Genome Resources, Apr 2022]