Sec63 - SEC63-like (S. cerevisiae)

Predicted to enable protein transmembrane transporter activity. Acts upstream of or within several processes, including liver development; multicellular organism aging; and protein targeting to ER. Predicted to be located in endoplasmic reticulum and membrane. Predicted to be part of Sec62/Sec63 complex. Is expressed in several structures, including adrenal gland; brain; cardiovascular system; genitourinary system; and pancreas. Human ortholog(s) of this gene implicated in polycystic liver disease. Orthologous to human SEC63 (SEC63 homolog, protein translocation regulator). [provided by Alliance of Genome Resources, Apr 2022]