Predicted to enable several functions, including cholesterol binding activity; enzyme activator activity; and heparin binding activity. Involved in animal organ regeneration; lipid transport; and response to hormone. Located in extracellular space. Biomarker of hypothyroidism. Human ortholog(s) of this gene implicated in cerebral infarction; coronary artery disease; familial hyperlipidemia (multiple); and type 2 diabetes mellitus. Orthologous to human APOA5 (apolipoprotein A5). [provided by Alliance of Genome Resources, Apr 2022]