F2rl1 - coagulation factor II (thrombin) receptor-like 1

Enables G protein-coupled receptor activity; G-protein alpha-subunit binding activity; and G-protein beta-subunit binding activity. Involved in several processes, including mature conventional dendritic cell differentiation; positive regulation of cytokine production; and positive regulation of intracellular signal transduction. Located in pseudopodium. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; sensory organ; and skin. Human ortholog(s) of this gene implicated in asthma; chronic obstructive pulmonary disease; and respiratory allergy. Orthologous to human F2RL1 (F2R like trypsin receptor 1). [provided by Alliance of Genome Resources, Apr 2022]