Eya4 - EYA transcriptional coactivator and phosphatase 4

Predicted to enable protein tyrosine phosphatase activity. Acts upstream of or within middle ear morphogenesis and sensory perception of sound. Predicted to be located in cytoplasm. Predicted to be active in nucleus. Is expressed in several structures, including alimentary system; embryo mesenchyme; limb bud; sensory organ; and urinary system. Used to study otitis media. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 10; congestive heart failure; dilated cardiomyopathy; dilated cardiomyopathy 1J; and sensorineural hearing loss. Orthologous to human EYA4 (EYA transcriptional coactivator and phosphatase 4). [provided by Alliance of Genome Resources, Apr 2022]