Slc8a2 - solute carrier family 8 member A2

Enables calcium:cation antiporter activity involved in regulation of postsynaptic cytosolic calcium ion concentration and calcium:sodium antiporter activity. Involved in inorganic cation transmembrane transport; response to vitamin D; and telencephalon development. Acts upstream of or within cellular calcium ion homeostasis. Located in several cellular components, including dendritic spine; microtubule; and neuronal cell body. Is active in postsynapse. Is integral component of mitochondrial membrane and integral component of postsynaptic membrane. Biomarker of brain ischemia and status epilepticus. Orthologous to human SLC8A2 (solute carrier family 8 member A2). [provided by Alliance of Genome Resources, Apr 2022]