Ext2 - exostosin glycosyltransferase 2

Enables acetylglucosaminyltransferase activity; glucuronosyltransferase activity; and protein homodimerization activity. Acts upstream of or within with a positive effect on gene expression; protein N-linked glycosylation; and sulfation. Acts upstream of or within several processes, including heparan sulfate proteoglycan biosynthetic process; heparin biosynthetic process; and sodium ion homeostasis. Located in Golgi apparatus and endoplasmic reticulum. Is expressed in several structures, including alimentary system; central nervous system; ear; genitourinary system; and respiratory system. Used to study hereditary multiple exostoses. Orthologous to human EXT2 (exostosin glycosyltransferase 2). [provided by Alliance of Genome Resources, Apr 2022]