Enables protein homodimerization activity. Involved in several processes, including positive regulation by host of viral genome replication; positive regulation of protein targeting to membrane; and regulation of acid-sensing ion channel activity. Located in mitochondrion and perinuclear region of cytoplasm. Is integral component of plasma membrane. Is expressed in bladder; gut; and liver lobe. Orthologous to human STOM (stomatin). [provided by Alliance of Genome Resources, Apr 2022]