Enah - ENAH actin regulator

Enables SH3 domain binding activity and profilin binding activity. Involved in actin filament organization and actin polymerization-dependent cell motility. Acts upstream of or within actin polymerization or depolymerization; cellular response to leukemia inhibitory factor; and nervous system development. Located in several cellular components, including focal adhesion; lamellipodium; and stress fiber. Is expressed in several structures, including branchial arch; early embryo; gonad; limb bud; and nervous system. Orthologous to human ENAH (ENAH actin regulator). [provided by Alliance of Genome Resources, Apr 2022]