Efna1 - ephrin A1

Enables ephrin receptor binding activity. Involved in several processes, including heart valve morphogenesis; negative regulation of dendritic spine morphogenesis; and regulation of blood vessel endothelial cell migration. Acts upstream of or within several processes, including ephrin receptor signaling pathway; nervous system development; and regulation of MAPK cascade. Is anchored component of plasma membrane. Is expressed in several structures, including alimentary system; brain; cardiovascular system; genitourinary system; and sensory organ. Orthologous to human EFNA1 (ephrin A1). [provided by Alliance of Genome Resources, Apr 2022]