Eed - embryonic ectoderm development

Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and chromatin binding activity. Acts upstream of or within several processes, including cellular response to leukemia inhibitory factor; regulation of adaxial/abaxial pattern formation; and regulation of gene expression. Located in pronucleus and sex chromatin. Part of ESC/E(Z) complex and chromatin silencing complex. Is expressed in several structures, including branchial arch; early embryo; extraembryonic component; genitourinary system; and nervous system. Orthologous to human EED (embryonic ectoderm development). [provided by Alliance of Genome Resources, Apr 2022]