Ebf1 - early B cell factor 1

Enables DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in positive regulation of transcription by RNA polymerase II. Acts upstream of or within positive regulation of transcription, DNA-templated. Located in nucleus. Is expressed in several structures, including central nervous system; genitourinary system; integumental system; limb mesenchyme; and sensory organ. Used to study lipodystrophy. Orthologous to human EBF1 (EBF transcription factor 1). [provided by Alliance of Genome Resources, Apr 2022]