Enables deoxyribonuclease II activity. Acts upstream of or within DNA catabolic process, endonucleolytic; erythrocyte differentiation; and regulation of immune response. Predicted to be located in lysosome. Is expressed in olfactory epithelium and vibrissa. Used to study rheumatoid arthritis. Orthologous to human DNASE2 (deoxyribonuclease 2, lysosomal). [provided by Alliance of Genome Resources, Apr 2022]