Enables endonuclease activity. Involved in several processes, including DNA catabolic process, endonucleolytic; neutrophil activation involved in immune response; and regulation of neutrophil mediated cytotoxicity. Acts upstream of or within apoptotic DNA fragmentation and programmed cell death involved in cell development. Located in nucleus. Orthologous to human DNASE1L3 (deoxyribonuclease 1 like 3). [provided by Alliance of Genome Resources, Apr 2022]