Ackr1 - atypical chemokine receptor 1 (Duffy blood group)

Predicted to enable C-C chemokine binding activity. Acts upstream of or within inflammatory response and regulation of chemokine production. Predicted to be located in endosome and membrane. Predicted to be integral component of membrane. Is expressed in several structures, including genitourinary system; hemolymphoid system; lung; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in Plasmodium vivax malaria and malaria. Orthologous to human ACKR1 (atypical chemokine receptor 1 (Duffy blood group)). [provided by Alliance of Genome Resources, Apr 2022]