Predicted to enable CCR6 chemokine receptor binding activity and identical protein binding activity. Involved in innate immune response and response to bacterium. Predicted to be located in microvesicle and sperm midpiece. Predicted to be extrinsic component of membrane. Predicted to be active in extracellular space. Is expressed in epidermis and skin. Human ortholog(s) of this gene implicated in asthma; chronic obstructive pulmonary disease; and lung disease. Orthologous to human DEFB1 (defensin beta 1). [provided by Alliance of Genome Resources, Apr 2022]