Asap1 - ArfGAP with SH3 domain, ankyrin repeat and PH domain1

Enables GTPase activator activity; SH3 domain binding activity; and phospholipid binding activity. Acts upstream of or within negative regulation of dendritic spine development; positive regulation of membrane tubulation; and positive regulation of podosome assembly. Located in cell projection membrane; dendritic spine; and podosome. Is active in cytosol and plasma membrane. Is expressed in several structures, including gonad; limb; long bone; perichondrium; and thoracic duct. Orthologous to human ASAP1 (ArfGAP with SH3 domain, ankyrin repeat and PH domain 1). [provided by Alliance of Genome Resources, Apr 2022]