Dab1 - disabled 1

Predicted to enable phosphatidylinositol 3-kinase binding activity. Involved in lateral motor column neuron migration. Acts upstream of or within several processes, including adult walking behavior; negative regulation of receptor signaling pathway via JAK-STAT; and nervous system development. Located in perinuclear region of cytoplasm. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in spinocerebellar ataxia type 37. Orthologous to human DAB1 (DAB adaptor protein 1). [provided by Alliance of Genome Resources, Apr 2022]