Csf2rb - colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)

Predicted to enable cytokine receptor activity. Acts upstream of or within cytokine-mediated signaling pathway and regulation of cell growth. Predicted to be located in membrane. Predicted to be integral component of membrane. Is expressed in several structures, including bone marrow; cardiovascular system mesenchyme; dorsal aorta; genitourinary system; and yolk sac. Used to study pulmonary alveolar proteinosis. Human ortholog(s) of this gene implicated in pulmonary alveolar proteinosis. Orthologous to human CSF2RB (colony stimulating factor 2 receptor subunit beta). [provided by Alliance of Genome Resources, Apr 2022]