Cr1l - complement component (3b/4b) receptor 1-like

Predicted to enable complement receptor activity and opsonin binding activity. Acts upstream of or within several processes, including cellular response to hypoxia; complement activation; and negative regulation of complement activation. Located in basolateral plasma membrane and external side of plasma membrane. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system; and liver and biliary system. Human ortholog(s) of this gene implicated in malaria. Orthologous to several human genes including CR1L (complement C3b/C4b receptor 1 like). [provided by Alliance of Genome Resources, Apr 2022]