Enables coproporphyrinogen oxidase activity. A structural constituent of eye lens. Acts upstream of or within heme biosynthetic process. Located in membrane and mitochondrion. Is expressed in embryo and yolk sac. Used to study hereditary coproporphyria. Human ortholog(s) of this gene implicated in hereditary coproporphyria and liver disease. Orthologous to human CPOX (coproporphyrinogen oxidase). [provided by Alliance of Genome Resources, Apr 2022]