Cobl - cordon-bleu WH2 repeat

Enables actin monomer binding activity. Involved in actin filament organization; collateral sprouting in absence of injury; and positive regulation of cell projection organization. Acts upstream of or within several processes, including chordate embryonic development; liver development; and notochord development. Located in several cellular components, including growth cone; ruffle; and terminal web. Colocalizes with actin filament. Is expressed in several structures, including central nervous system; chordamesoderm; embryo mesenchyme; gut; and nose. Orthologous to human COBL (cordon-bleu WH2 repeat protein). [provided by Alliance of Genome Resources, Apr 2022]